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BMCS Hot Topics: Peptides in Drug Discovery

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BMCS Hot Topics: Peptides in Drug Discovery

Date

6 May 2026

Subject areas

Chemical Biology and Medicinal

Location

Online

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Synopsis The BMCS Hot Topics online meetings are intended to highlight breaking areas of research in fields of science relevant to drug discovery. They will run as stand-alone half-day virtual events, 2-3 times per year. The programme will be targeted towards researchers working who would like to enhance their understanding of these nascent or developing fields.

Peptides are a key modality for modulating biological pathways with the potential to enable mechanisms inaccessible to traditional small molecules. This meeting will showcase advances in peptide discovery and development, from cyclic and stapled scaffolds to strategies for achieving oral bioavailability. Talks will span discovery and optimisation technologies alongside chemistry strategies for stability, permeability, and delivery, with case studies charting progress from peptide leads to clinical candidates.

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Registration Registration is open. PleaseÌýÌýto register.

Please note that registrations are for one person per booking.

If you wish to register multiple people from the same organisation, we can offer a sizeable discount. If you are interested, please contact [email protected].

Registration fees: RSC Member: £55.00 Non-Member: £75.00 RSC Student Member: £40.00 Student Non-Member: £50.00

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Want to become a member? To join the RSC in order to qualify for discounted registration fees at all RSC, please follow thisÌýRSC link.

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Sponsorship The organising committee are seeking sponsorship from organisations supporting the low registration fees offered to students. If you wish to sponsor, pleaseÌý.

All sponsors will receive the following: – Logo and URL on the meeting website – Logo on the holding slides shown during the breaks at the meeting – Logo included in the delegate handbook – One static slide to be included in the holding slides

Programme

All times quoted are UK Time.

13:00 Opening Remarks
Ìý Session Chair: Marta Brambilla, Johnson & Johnson
13:05 Pius Baur, Johnson & Johnson Peptides as Biological Therapeutics: Fundamentals & Future Directions
13:45 Nick Lewis, Bicycle Therapeutics Bicycle®-peptoid hybrids for antimicrobial discovery
14:20 Poppy Llowarch, AstraZeneca Accelerating peptide hit-to-lead optimisation using affinity-selection mass spectrometry
14:55 Break
Ìý Session Chair: Hannah Fowler, RSC
15:15 Christian Heinis, École Polytechnique Fédérale de Lausanne (EPFL) Developing membrane-permeable cyclic peptides
15:50 Jennifer Johnston, Merck Discovery of Enlicitide: from mRNA display to Phase II
16:25 Jim Aggen, Circle Pharma Cyclin A/B RxL Inhibitors: A case study for achieving cell permeability and oral bioavailability in macrocyclic peptides
17:00 Closing Remarks
17:05 Close of Conference

Speakers

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Pius Baur

Johnson & Johnson

Switzerland

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Nick Lewis

Bicycle Therapeutics

UK

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Poppy Llowarch

AstraZeneca

UK

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Christian Heinis

École Polytechnique Fédérale de Lausanne (EPFL)

Switzerland

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Jennifer Johnston

Merck

United States

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Jim Aggen

Circle Pharma

United States

Committees

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Adrian Hall

UCB

Belgium

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Daniel O Donovan

AstraZeneca

UK

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Chris Swain

Cambridge MedChem Consulting

UK

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Hannah Fowler

RSC

UK

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Louise Walport

Imperial College

UK

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Marta Brambilla

Johnson & Johnson

Belgium

Event details

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Hg3 Conferences Ltd

Hg3 Conferences Ltd

4 Dragon Road Harrogate HG1 5DF

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